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What is the difference between betaine series surfactants?

2025-10-21

*Cocamidopropyl Betaine

It is a gentle amphoteric surfactant, can be compatible with all surfactants, and is the most common product on the market.

With excellent foaming and thickening properties, it effectively reduces irritation in the entire formula. It provides hair conditioning benefits under weakly acidic pH conditions. Suitable for use in shampoos, bath cleansers, and baby products.

The foam of cocamidopropyl betaine is dense and fluffy. When combined with anionic surfactants, it enhances and stabilizes foam while also thickening the formula. It provides a silky-smooth texture and is suitable for transparent formulations. However, excessive use may result in artificial slip.

*Cocamidopropyl Hydroxysulfonate Betaine

Similar to cocamidopropyl betaine, it is a gentle amphoteric surfactant that helps thicken, reduce irritation, and condition hair. However, it differs in that Cocamidopropyl Hydroxysulfonate Betaine produces a denser foam, exhibits lower irritation, and demonstrates better hard water resistance. Within appropriate dosage ranges, it is also suitable for transparent formulations.

*Lauryl Hydroxysultaine Betaine

As one of the gentlest betaine-based surfactants, it demonstrates excellent salt tolerance, hard water resistance, and stable performance even at low temperatures. When combined with amino acid surfactants like sodium sarcosinate and sodium taurate, it achieves remarkable thickening effects, effectively addressing the common thickening challenges faced by amino acid surfactants. The product offers a refreshing cleansing sensation, and its synergistic application helps reduce the artificial slipperiness often associated with similar formulations.

*Summary:

Common: The betaine series of surfactants have low irritation, excellent foaming performance, thickening effect on the formula, and a certain effect on hair conditioning and softness.

Properties:

Cocamidopropyl Betaine: The most common amphoteric surfactant, the market use is very large, excellent foaming and thickening properties, it has a certain softening effect under weak acid conditions.
Cocamidopropyl Hydroxysulfonate Betaine: A good choice for formulations that require lower irritation, denser foam, and better hard water resistance. It is suitable for making baby products.
Lauryl Hydroxysultaine Betaine: Suitable for formulations containing amino acid surfactants and formulations with high salt tolerance requirements. It is also cold resistant.

Comparison of irritation of several common surfactants:

Test method: Corn alcohol-soluble protein method @1% active substance

1: Lauramidopropyl Hydroxysultaine Betaine

2: Cocamidopropyl Hydroxysultaine Betaine

3: Lauryl Hydroxysultaine Betaine

4: Lauryl Betaine

5: Disodium Cocoamphodiacetate

6: Cocamidopropyl Betaine

7: Lauramidopropyl Betaine

8: Sodium Lauroamphoacetate

9: Monoglycidylamine oxide

10: potassium Laureth Phosphate

11: Sodium Lauroyl Sarcosinate

12: Disodium Lauryl Sulfosuccinate

13: Ammonium Laureth Sulfate

14: Sodium Lauryl Sulfate

15: SLES